Test by Methodology - Immunohistochemistry (IHC)

329 Tests in Listing


AACT

This antibody labels the cytoplasm of histiocytes and neoplasms of histiocytic origin, as well as monocytes and macrophages of human colon, tonsil and...

IHC

AAT

Alpha-1-Antitrypsin (AAT) is useful in the study of inherited AAT deficiency, benign and malignant hepatic tumors and yolk sac carcinoma. Sensitivity ...

IHC

ACTH

Anti-adrenocorticotropic hormone (ACTH) is a useful marker in the classification of pituitary tumors and the study of pituitary disease. It reacts wit...

IHC

Adenovirus

Adenoviruses are simple DNA-containing viruses that multiply in the cell nucleus. They induce latent infections in tonsils, adenoids and other lympho...

IHC

AFB

Special stain. Ziehl-Neelsen Acid-Fast Bacilli Stain is used to detect the presence of acid-fast mycobacteria in tissue sections. Acid-fast techniques...

IHC

AFP

Alpha-1-fetoprotein (AFP) is a 64 kD tumor-associated embryonal antigen produced by fetal liver, hepatocellular carcinoma, yolk sac tumor and several ...

IHC

Alcian Blue

Special stain. Alcian blue is intended to identify weakly sulfated mucins in tissue samples.

IHC

ALK (D5F3)

VENTANA FDA approved ALK (D5F3) CDx Assay is intended for the qualitative detection of the anaplastic lymphoma kinase (ALK) protein in formalin-fixed,...

IHC

ALK-1 (for heme cases)

The ALK1 (ALK1 cline) antibody labels normal human ALK protein and the NPM-ALK chimeric protein, and is a useful tool for the identification of the su...

IHC

Alpha Synuclein

Alpha-Synuclein is the major component of Lewy bodies and Lewy neuritis in sporadic Parkinson disease, dementia with Lewy bodies and the Lewy body var...

IHC

Amyloid A

This antibody reacts with amyloid deposits in all formalin-fixed, paraffin embedded (FFPE) tissues, including kidney and rectum.

IHC

Amyloid P

Amyloid P component reacts with all types of amyloid deposits, however, it is also present in normal elastic tissue and basement membranes. The appl...

IHC

Annexin A1

Annexin A1 (ANXA1), a gene related to phagocytosis, is found to be one of the most highly upregulated genes in hairy cell leukemia. Annexin A1 is stro...

IHC

AR

Androgen receptor (AR) is responsible for the regulation of the growth of the prostate epithelial cells. In untreated prostate carcinoma, AR positive ...

IHC

Arginase 1

Arginase 1 (ARG1), also known as liver arginase, is a binuclear manganese metalloenzyme. ARG1 is abundantly expressed in liver and represents a sensit...

IHC

B72.3

This monoclonal antibody (B72.3) to tumor-associated glycoprotein recognizes a tumor-associated oncofetal antigen (TAG-72) expressed by a wide variety...

IHC

BAP1

BAP1 IHC stain is a tool for detection of BAP1 mutations with subsequent inactivation. Loss of BAP1 by IHC is 100% specific for malignant mesothel...

IHC

BCA-225

This antibody recognizes a human breast carcinoma associated glycoprotein BCA-225 (220-225kD). This protein differs in size and distribution from othe...

IHC

BCL1/Cyclin D1

BCL1/Cyclin D1 is a nuclear protein detectable in formalin-fixed, paraffin-embedded (FFPE) sections and is found in the majority of mantle cell lympho...

IHC

BCL2

B-cell lymphoma 2 (BCL2) was the first of the translocation-associated proteins to be identified in lymphoma. Most cases of follicular lymphoma have ...

IHC

BCL6

BCL6 antibody stains the germinal center cells in lymphoid follicles, the follicular cells and interfollicular cells in follicular lymphoma, a subset ...

IHC

BerEP4

Ber-EP4 recognizes two glycoproteins of 34 and 49 kDa present on the surface and the cytoplasm of all epithelial cells except the superficial layers ...

IHC

Beta Amyloid

Beta amyloid is an extracellular filamentous protein deposit found in Alzheimer's disease brain tissue. It is the major protein component of amyloid ...

IHC

Beta Catenin

Beta-catenin is an important regulator of cell–cell adhesion and embryogenesis. Mutations of beta-catenin could lead to some human cancers. Normal cel...

IHC

BG8

This antibody is specific for the Lewis Y (Type 2 Chain) carbohydrate antigen. Lewis Y has been evaluated as a clinical marker for the diagnosis and p...

IHC

BOB1

BOB1 is present in all B-cells expressing Ig. The combination of BOB1 and OCT2 staining is helpful in distinguishing between classical Hodgkin lymphom...

IHC

BRAF V600E

A monoclonal antibody (VE1) against mutant BRAF (V600E) permits fast assessment of the mutant protein expression throughout a tumor sample in hairy ce...

IHC

BRCA1

BRCA1 (breast and ovarian cancer susceptibility protein 1) is a nuclear phosphoprotein that plays a role in maintaining genomic stability and acts as ...

IHC

Breast Triple Stain (CK5 + p63 + CK 8/18)

The combination of CK5 + P63 + CK8/18 (Breast Triple Stain) can be useful in distinguishing ductal carcinoma in situ (DCIS) from microinvasive breast ...

IHC

CA125

CA125 reacts with most epithelial ovarian neoplasms of serous, endometrioid, clear cell and undifferentiated types. CA125 is a useful tumor marker for...

IHC

CA19.9

In normal tissues, the CA19.9 antigen has been demonstrated in ductal epithelium of the breast, kidney, salivary gland, sweat glands, respiratory epit...

IHC

Calcitonin

Calcitonin is secreted by thyroidal parafollicular cells of neuroectodermal origin, probably in response to hypercalcemia. The IHC demonstration of ca...

IHC

Calcium Stain

Special stain.

IHC

Caldesmon

Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction. Two closely related variants of human caldesmon...

IHC

Calponin

Calponin, a calmodulin, is involved in the regulation of smooth muscle contraction. The expression of calponin is restricted to smooth muscle cells. T...

IHC

Calretinin

Calretinin is the most specific and reproducible positive marker of epithelial mesothelioma. Calretinin is a calcium-binding protein similar to S100 p...

IHC

CAM 5.2 (CK LMW)

Anti-Cytokeratin (CAM 5.2) has a primary reactivity with human keratin proteins that correspond to Moll`s peptides #7 and #8, Mr 48 and 52 Kd. Cytoker...

IHC

Carbonic Anhydrase IX (CA IX)

Carbonic anhydrase IX (CAIX) is a cell surface transmembrane protein, which is predominantly found in the gastrointestinal tract and gall bladder. The...

IHC

Cat Scratch

The causative bacterial agent of cat scratch disease has been identified as Bartonella henselae. This monoclonal antibody identifies bartonella hensel...

IHC

Cathepsin D

Cathepsin D is an estrogen-regulated lysosomal protease that has been suggested to facilitate cancer cell migration and invasion by digesting the base...

IHC

CD10

CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA), is expressed in early lymphoid progenitors and normal germinal center cells. It...

IHC

CD117 cKIT

CD117 (cKit) is a transmembrane receptor tyrosine kinase. It is expressed in many tissues and cells, such as tissue mast cells, skin basal cells, mela...

IHC

CD11c

In normal cells, CD11c is expressed on activated CD4/CD8+ T cells, granulocytes, lymphocytes, macrophages, and NK cells.

In diseased, c...

IHC

CD123

CD123 labels plasmacytoid dendritic cells and is useful in diagnosing neoplasms derived from these cells as well as reactive conditions, such as hist...

IHC

CD138

CD138 (Syndecan-1) positively stains normal tissue including B-cell precursors and plasma cells. Positive staining in tumors includes myeloma, primary...

IHC

CD14

CD14 stains normal macrophages/monocytes, granulocytes (weak), Langerhans cells, dendritic cells, and B cells. Positive staining in diseased cells c...

IHC

CD15

CD15 (X-Hapten) plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on granulocytes, including neutrophils an...

IHC

CD163

CD163 antigen is restricted in its expression to the monocytic/macrophage lineage. It is present on all circulating monocytes and most tissue macropha...

IHC

CD19

CD19 recognizes a 95kD cell surface glycoprotein which is expressed by cells of the B-cell lineage and follicular dendritic cells. CD19 is a co-recep...

IHC

CD1a

At least five CD1 genes (CD1a, b, c, d, and e) have been identified. CD1a is expressed on cortical thymocytes, Langerhans cells, and dendritic cells. ...

IHC

CD2

CD2, the E-rosette receptor, is an extremely broad T-cell marker. This antibody immunostains the vast majority of T-cells and a subset of natural kill...

IHC

CD20

Normal cell expression of CD20 is found on most B-cells (after CD19 and CD10 expression, before CD21/22 expression and surface immunoglobulin express...

IHC

CD21

CD21 (CR2, C3d receptor and EBV receptor) is expressed strongly on mature B-cells, follicular dendritic cells (FDC) and weakly on immature thymocytes ...

IHC

CD22

CD22 expression is restricted to normal and neoplastic B-cells and is absent from other hemopoietic cell types. In B-cell ontogeny, CD22 is first expr...

IHC

CD23

CD23 is identical to low affinity IgE receptor found on B-cells. CD23 is expressed on a subpopulation of peripheral blood cells, B-lymphocytes and on ...

IHC

CD25

The interleukin-2 receptor is designated CD25. Originally isolated from T-lymphocytes, it is now known to be expressed on hairy cell leukemia and adu...

IHC

CD3

The CD3 antigen is first detectable in early thymocytes and its appearance probably represents one of the earliest signs of commitment to the T-cell l...

IHC

CD30

CD30 is a lymphocyte activation antigen, related to tumor necrosis factor. It is expressed in activated B-, T- and NK cells. Positive staining is seen...

IHC

CD31

CD31 is a 130kDa transmembrane glycoprotein that is shared by vascular lining cells, megakaryocytes and platelets. This marker is highly restricted to...

IHC

CD33

CD33 is a useful marker to identify cells of myeloid and monocytic lineage, leukemias and myeloproliferative neoplasms derived from these cells.

IHC

CD34

CD34, a single chain transmembrane glycoprotein, is selectively expressed on human lymphoid and myeloid hematopoietic progenitor cells and endothelial...

IHC

CD35

CD35 antigen is a transmembrane protein of 160-250 kDa that binds complement components C3b and C4b. It mediates phagocytosis by neutrophils and mono...

IHC

CD38

CD38 is a transmembrane protein that is highly expressed on thymocytes. It is also present on activated T-cells and terminally differentiated B-cells ...

IHC

CD4

CD4, a single chain transmembrane glycoprotein, is found on a T-cell subset (helper/inducer). It is also present on a variety of monocyte-derived cell...

IHC

CD42b

CD42b stains normal platelets, megakaryocytes, and megakaryoblasts. In diseased cells, blasts in transient myeloproliferative disorder are positively ...

IHC

CD43

CD43 (leukosialin, sialophorin, or leukocyte sialoglycoprotein) is a cell surface glycoprotein that is expressed on all thymocytes, T-cells, and cells...

IHC

CD44

The CD44 family of glycoproteins exists in a number of variant isoforms, including hematopoietic variant (CD44s) and epithelial cells variant (CD44v)....

IHC

CD45 (LCA)

CD45 (Leukocyte Common Antigen, LCA) is comprised of at least four isoforms (CD45RA, CD45RB, CD45RC and CD45RO) of membrane glycoproteins. CD45 is exp...

IHC

CD45RB

CD45RB, an isoform of CD45 with exon 5 splicing (encodes B determinant), is expressed on mature B- and T-lymphocytes and a majority of lymphomas and l...

IHC

CD45RO

CD45RO (an isoform of leukocyte common antigen) reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within ...

IHC

CD5

CD5, a transmembrane protein, is found on most thymocytes and immature peripheral T-cells. It stains normal B-cells of mantle zone of spleen and lymph...

IHC

CD56

CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally-derived cell lines, tissues ...

IHC

CD57

CD57 is expressed on subpopulations of peripheral blood mononuclear cells, NK active cells and T-cells. Hematopoietic malignancies that are CD57+ incl...

IHC

CD61

CD61 (GPIIIa) is a glycoprotein found on megakaryocytes, platelets, and their precursors. CD61 antigen plays a role in platelet aggregation and also a...

IHC

CD68

CD68 is an antibody directed against lysosomes. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variet...

IHC

CD7

CD7 is expressed on the majority of immature and mature T-lymphocytes and T-cell leukemia. It is also found on natural killer cells, and a small subpo...

IHC

CD71

CD71 is useful in identifying erythroid precursors with no interference from mature erythrocytes and also in the determination of erythroid leukemia, ...

IHC

CD79a

CD79a first appears at the pre B-cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found ...

IHC

CD8

CD8 is a T-cell marker for the detection of cytotoxic/suppressor T-cells. CD8 is also detected on NK cells, most thymocytes, a subpopulation of null c...

IHC

CD99

CD99 (MIC2 gene product, E2) antigen is strongly expressed by Ewing sarcoma cells, primitive peripheral neuroectodermal tumors, and lymphoblastic leuk...

IHC

CDK4

Among cyclin/CDK proteins, CDK4 and cyclin D1 are the most frequently activated by somatic genetic alterations in multiple tumor types. CDK4 antibody...

IHC

CDX2

CDX2 is an intestine specific transcription factor that regulates both the proliferation and differentiation of intestinal epithelial cells. It is exp...

IHC

CDX2/CK7 Double Stain

CDX2 is a transcription factor expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum. The CDX2 protein is expr...

IHC

CEA (Mono)

Carcinoembryonic antigen (CEA) is usually demonstrated as a linear labeling of the apical poles of cells lining the glandular lumen and occasionally a...

IHC

CEA (Poly)

Polyclonal carcinoembryonic antigen (CEA) antibody stains a larger percentage of cholangiocarcinomas compared to hepatocellular carcinomas. Approxima...

IHC

Chromogranin A

Chromogranin is present in several elements of the diffuse neuroendocrine system (DNES), including anterior pituitary, thyroid perifollicular C cells,...

IHC

CK 10/13 (Cytokeratin 10/13)

Cytokeratins 10 and 13 are intermediate-size, acidic type I cytokeratins (molecular mass of 56.5 kDa). CK10/13 cocktail is expressed in all suprabasa...

IHC

CK AE1/AE3

Monoclonal antibodies AE1 and AE3 recognize the acidic and basic subfamilies of cytokeratin, respectively, thus the combination of these two antibodie...

IHC

CK HMW (CK903/34BE12)

CK903 (34betaE12) is a high molecular weight cytokeratin present in all squamous epithelium and their carcinomas. This antibody recognizes cytokeratin...

IHC

CK HMW/CK LMW Double Stain

This cytokeratin cocktail can be useful in differentiation of the squamous cell carcinomas and adenocarcinomas. The 34bE12 clone recognizes cytokerat...

IHC

CK OSCAR

Anti-cytokeratin clone OSCAR (CK OSCAR) demonstrates a broad spectrum of cytokeratin reactivity. In normal tissues, OSCAR is reactive with most epithe...

IHC

CK14 (Cytokeratin 14)

Cytokeratin 14 (CK14) belongs to the type A (acidic) subfamily of high molecular weight keratins and exists in combination with keratin 5. CK14 has be...

IHC

CK17

Cytokeratin 17 (CK17) is an effective marker to distinguish myoepithelial cells from luminal epithelium of various glands (mammary, sweat, salivary, b...

IHC

CK18 (Cytokeratin 18)

Cytokeratin 18 (CK 18), a 45kDa protein, belongs to the acidic type of cytokeratins, and is typically expressed in simple, nonstratified epithelia. Ho...

IHC

CK19

Cytokeratin 19 (CK19) is a member of the type I acidic subfamily of keratins. It is expressed in various different human tissues. CK19 labels ductal ...

IHC

CK20

Cytokeratin 20 (CK20) positivity is seen in the majority of adenocarcinomas of the colon, mucinous ovarian carcinomas, transitional cell, and Merkel c...

IHC

CK5/6

D5/16 B4 clone of CK5/6 antibody reacts strongly with cytokeratins 5 and 6. Cytokeratin 5/6 have been found valuable for the distinction between low d...

IHC

CK7

Cytokeratin 7 (CK7) antibody reacts with proteins that are found in most ductal, glandular and transitional epithelium of the urinary tract and bile d...

IHC

cMET

The cMET tyrosine kinase receptor, normally expressed by epithelial cells, is overexpressed and amplified in a variety of human tumors, including non-...

IHC

CMV (Cytomegalovirus) by IHC

Cytomegalovirus (CMV) is an opportunistic pathogen infecting lung, kidney, gut and other organs in situations where an individual is immunologically ...

IHC

cMyc

cMyc protein is a transcription factor localized to the nucleus of the cell. Amplification of the cMyc gene has been found in several types of human ...

IHC

Collagen IV

Collagen IV is a major constituent of the basement membranes along with laminins and enactins. In kidney, the antibody reacts with glomerular and tubu...

IHC

Congo Red

Special stain.

IHC

Copper Stain

Special stain.

IHC

COX2

Cyclooxygenase-2 (COX-2) plays a role in tumorigenesis through stimulating epithelial cell proliferation, inhibiting apoptosis, stimulating angiogenes...

IHC

cREL

Inactive cREL resides in the cytoplasm and translocates to the nucleus upon activation. Strong, homogeneous nuclear cREL staining has been observed ...

IHC

CXCL13

CXCL13 is useful marker in the diagnosis of angioimmunoblastic T-cell lymphoma

IHC

CXCR4

CXCR4 is an important factor in the migration, invasiveness, metastasis and proliferation of breast cancer cells. The majority of breast cancers expre...

IHC

D240

D2 40 identifies a 40kDa O-linked sialoglycoprotein expressed by a variety of tissues, including fetal testes and testicular germ cell tumors. Anti-D2...

IHC

DBA.44

This antibody reacts with a subset of B-cells in the mantle zone and some immunoblasts outside the follicle. It reacts with most hairy cell leukemia c...

IHC

DCC (Deleted in Colorectal Cancer Protein)

The deleted in colorectal cancer (DCC) gene located on chromosome 18 is a tumor suppressor gene. The DCC gene is expressed in most epith...

IHC

Desmin

Desmin is an intermediate filament protein of both smooth and striated muscles. Antibody to desmin reacts with striated (skeletal and cardiac) as well...

IHC

DOG1

DOG1 is a cell surface protein of unknown function selectively expressed in gastrointestinal stromal tumors (GIST). Among GIST cases with Kit mutation...

IHC

DPC4

The gene DPC4 (deleted in pancreatic carcinoma 4, also called SMAD4) was identified in 18q21.3 This gene is frequently mutated and deleted in p...

IHC

EBV (LMP1)

This antibody reacts strongly with Epstein Barr Virus (EBV)-positive lymphoblastoid cell lines and EBV infected B-cell immunoblasts in infectious mono...

IHC

E-Cadherin

E Cadherin is an adhesion protein that is expressed in cells of epithelial lineage. It stains positively in glandular epithelium, as well as adenocarc...

IHC

EGFR

Epidermal Growth Factor Receptor (EGFR) overexpression can occur in a variety of tumor types, including breast, prostate, ovarian, brain, lung and pre...

IHC

EGFR (E746-A750del specific)

Epidermal Growth Factor Receptor (EGFR) is a 170 kDa transmembrane receptor tyrosine kinase that belongs to the HER/ErbB protein family. Somatic mutat...

IHC

EGFR (L858R mutant specific)

Epidermal Growth Factor Receptor (EGFR) is a 170 kDa transmembrane receptor tyrosine kinase that belongs to the HER/ErbB protein family. Somatic mutat...

IHC

eIF4E

eIF4E is a key regulator of translation of many cancer-related transcripts and its expression is altered in various cancers and has been associated w...

IHC

Elastic Stain

Special stain.

IHC

EMA

Epithelial Membrane Antigen (EMA) antibody stains normal and neoplastic cells from various tissues, including mammary epithelium, sweat glands and squ...

IHC

ER

Estrogen Receptor (ER) belongs to a superfamily of nuclear hormone receptors and is expressed in about 85% of invasive breast cancers. There are two ...

IHC

ERCC1

The Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 1 (ERCC1) polypeptide is required for nucleotide excision repa...

IHC

ERG

ERG oncoprotein expression has been shown to be a highly specific marker for prostate cancer. Given the lack of ERG expression in a wide variety of no...

IHC

Factor VIII RA

Factor VIII-related antigen is a component of Factor VIII complex. Factor VIII-related antigen is one of the available immunohistochemical markers of ...

IHC

Factor XIIIa

Factor XIIIa is a dermal dendrocyte marker and shows variable reaction with these types of tumors. It can be used for histiocytic phenotyping and has ...

IHC

Fascin

Human fascin is a highly conserved actin-bundling protein. It is expressed predominantly in dendritic cells. Lymphoid cells, myeloid cells and plasma ...

IHC

FLi-1

Friend leukemia integration (FLI1) is a nuclear transcription factor and has been reported as the first nuclear marker of endothelial differentiation....

IHC

Fontana Masson

Special stain.

IHC

FOXP1

FOX P1 (Forkheadbox-P1) is a transcription factor widely expressed in normal tissues. Its expression is commonly deregulated in malignancies. FOX P1 ...

IHC

FOXP3

FOX P3 is expressed at a high level in CD25 positive/CD4 positive regulatory T cells, at a low level in CD4 positive/CD25 negative cells, and is absen...

IHC

FSH

Follicle Stimulating Hormone (FSH) is a pituitary hormone involved in the maturation of ovarian follicles and estrogen secretion in females. In the p...

IHC

Galectin 3

Galectins are a structurally-related family of proteins; 14 different galectins have been characterized. They are cytoplasmic proteins and can be tra...

IHC

Gastrin

Gastrin, a polypeptide hormone, occurs naturally in three forms: gastrin-14, gastrin-17 and gastrin-34. This antibody labels gastrin or gastrin-analog...

IHC

GATA3

GATA3 (GATA binding protein 3) is a member of the GATA family of transcription factors. Among several other roles, GATA3 is involved in luminal cell ...

IHC

GCDFP15

This antibody is specific to a 15kDa monomer protein called Gross Cystic Disease Fluid Protein-15 (GCDFP-15). GCDFP15 is expressed in apocrine epithel...

IHC

GCET1

The GCET1 gene codes for a serpin expressed in germinal center (GC) B-cells. GCET1 is highly restricted to a subset of GC B-cells and GC-derive...

IHC

GFAP

Glial Fibrillary Acidic Protein (GFAP) is the major protein found in astrocytes and its expression is evidence of astroglial origin and differentiatio...

IHC

GH

Growth Hormone (GH) is produced by the somatotroph cells in the pituitary. This marker is a useful in classification of pituitary tumors and the st...

IHC

Glucagon

Glucagon antibody is used for the identification of tumors and hyperplasias of pancreatic islets. This antibody labels A cells of the endocrine mammal...

IHC

GLUT1

Glucose transporter 1 (GLUT1) facilitates the transport of glucose across the plasma membranes of mammalian cells. GLUT-1 is expressed in many human ...

IHC

Glutamine Synthetase

Glutamine synthetase (GS) is strongly expressed in a majority of hepatocellular carcinoma, including cases of early HCC and low grade HCC.

IHC

Glycophorin A

Glycophorin A (sialoglycoprotein alpha) is one of two transmembrane proteins exposed on the outer surface of normal human erythrocytes. This monoclona...

IHC

Glypican-3

A useful marker to differentiate between benign (negative) and malignant (positive) liver diseases (HCCs).

IHC

Granzyme B

Granzyme B antibody labels activated human cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. This marker can be a useful tool for the ident...

IHC

Grocott Methanamine Silver (GMS)

Special stain. GMS (Grocott Methenamine-Silver Nitrate) Fungus Stain is used to demonstrate fungal organisms in tissue sections.

IHC

GST Pi

Glutathione S Transferase Pi (GSTpi) is a cytosolic enzyme that catalyzes the conjugation of toxic compounds to glutathione for transport out of the c...

IHC

H. Pylori

This antibody reacts with H. pylori on the surface and in the cytoplasm of epithelial cells of stomach biopsies. Studies have shown that H. ...

IHC

Hall Bile Stain

Special stain.

IHC

HBME1

HBME1 is an anti-mesothelial monoclonal antibody that recognizes an unknown antigen on the microvilli of mesothelioma cells. It stains normal mesothel...

IHC

HCG-Beta (Human Chorionic Gonadotropin Beta)

HCG-beta is secreted in large quantities by the placenta and normally is found in maternal circulation during early fetal development. Polyclonal Rab...

IHC

Hemoglobin A

Hemoglobin A antibody reacts with the alpha chain of adult hemoglobin A. This antibody is useful in the detection of red blood cell precursors. Immuno...

IHC

Hepatitis B Core Antigen

Hepatitis B virus belongs to the hepatovirus family and causes type B hepatitis. Hepatitis B virus is spherical in shape with a diameter of 42 nm. Cor...

IHC

Hepatitis B Surface Antigen

Hepatitis B virus, belongs to the hepatovirus family, and causes type B hepatitis. It is spherical in shape with a diameter of 42 nm. It contains a 2...

IHC

HepPar1

Anti-Hepatocyte Specific Antigen (HepPar1) recognizes both benign and malignant liver derived tumors such as hepatoblastoma, hepatocellular carcinoma ...

IHC

HER2 Breast

This test uses the Ventana PATHWAY anti-HER-2/neu antibody (clone 4B5) for the semi-quantitative detection of HER-2 antigen in sections of FFPE normal...

IHC

HGAL

HGAL is specifically expressed in the cytoplasm of germinal center B-cells, but is absent in mantle and marginal zone. This antibody is highly specif...

IHC

HHV8

Human Herpes Virus (HHV) 8 is the likely etiological agent of Kaposi’s sarcoma (KS), and is present in all cases. HHV 8 encodes a latent nuclear ant...

IHC

HLADR

This antibody to the humn leukocyte antigen (HLA) MHC class II surface antigen stains a variety of cells expressing the HLADR antigen including B-lymp...

IHC

HMB45

Antibody clone HMB45 recognizes a melanoma-specific antigen by reacting with melanoma cells, nevus cells and neonatal melanocytes. HMB45 is expressed ...

IHC

HPL

Human Placental Lactogen (HPL) is a polypeptide hormone synthesized in syncytiotrophoblastic cells of placenta and has been used as a tissue marker fo...

IHC

HPV (Human Papilloma Virus) by IHC

Infection with specific types of Human Papilloma Virus (HPV) has been associated with an increased risk of developing cervical neoplasia. HPV types 6 ...

IHC

HSV I

This antibody reacts with Herpes Simplex Virus (HSV) type 1 specific antigens and with antigens common for HSV types 1 and 2. The antibody reacts with...

IHC

HSV II

This antibody reacts with Herpes Simplex Virus (HSV) type 2 specific antigens and with antigens common for HSV types 1 and 2. The antibody reacts with...

IHC

IDH1

IDH1 mutations are frequent genetic alterations in low-grade diffuse gliomas and secondary glioblastoma (70%). This alteration is observed in fewer...

IHC

IgA

IgA antibody reacts with immunoglobulin Ig alpha chains. It is useful in identifying leukemias, plasmacytomas and B-cell lineage lymphomas.

IHC

IgD

IgD antibody reacts with immunoglobulin Ig delta chains. This antibody is useful when identifying leukemias, plasmacytomas and B-cell lineage lymphoma...

IHC

IgG

IgG antibody reacts with immunoglobulin Ig gamma chains. This antibody may be useful in identifying plasma cytomas and B-cell lineage lymphomas, and ...

IHC

IgG4 (Immunoglobulin G4)

Autoimmune pancreatitis typically produces an enlarged pancreas with narrowing of the pancreatic duct, and can mimic carcinoma. It was shown that the ...

IHC

IgM

IgM antibody reacts with immunoglobulin Ig mu chains. This antibody is useful when identifying leukemias, plasmacytomas and B-cell lineage...

IHC

Inhibin

Anti-Inhibin alpha is an antibody against a peptide hormone which has a demonstrated utility in differentiating between adrenocortical tumors and rena...

IHC

INI1

Lack of nuclear expression of INI1 is characteristic of malignant rhabdoid tumors and epithelioid sarcomas.

IHC

Insulin

Insulin is composed of a and b chains connected through the C-peptide. The main storage site for insulin is the pancreatic islets. Antibodies to insul...

IHC

Kappa

Antibody to the kappa light chain of immunoglobulin is reportedly useful in the identification of leukemias, plasmacytomas and certain non-Hodgkin lym...

IHC

Ki67

Ki67 is a nuclear protein that is expressed in proliferating cells. Ki67 is preferentially expressed during late G1, S, M, and G2 phases of the cell ...

IHC

Ki67/Caspase 3 (Double Stain)

The Ki67/caspase-3 antibody cocktail was designed to provide information on apoptosis versus cell proliferation rates. The Ki67 is associated with cel...

IHC

Lambda (Lambda Light Chain IgG) by IHC

Antibody to the lambda light chain of immunoglobulin is reportedly useful in the identification of leukemias, plasmacytomas and certain non-Hodgkin ly...

IHC

Laminin

Anti-laminin, 4C7, antibody reacts with a 380kDa laminin alpha5 chain. This antibody stains proximal and distal tubuli, glomerular basement membrane, ...

IHC

Langerin

Langerin is a highly selective marker for Langerhans cells and the lesional cells of Langerhans cell histiocytosis. Langerin protein expression has ut...

IHC

LEF1

LEF1 overexpression is highly associated with CLL/SLL among small B-cell lymphomas and may serve as a useful marker for diagnosis and differential dia...

IHC

LH

Luteinizing Hormone (LH) is a tropic hormone that modulates the secretory activity of other endocrine glands. It is produced in the anterior hypophys...

IHC

LMO2

LMO2 protein is expressed in normal human germinal-center (GC) and GC-derived lymphomas. In addition, it is also expressed at high levels in endothel...

IHC

Lysozyme

Lysozyme is synthesized predominantly in reactive histiocytes rather than in resting, unstimulated phagocytes. This antibody labels myeloid cells, his...

IHC

Mammaglobin

Mammaglobin is a breast-associated glycoprotein. In normal breast tissue, this antibody labels breast ductal and lobular epithelial cells. In tumor c...

IHC

Masson Trichrome

Special stain.

IHC

MDR1 (Multi Drug Resistance Protein 1)

Multiple Drug Resistance Protein 1 (MDR1) is membrane protein associated with an efflux pump that actively removes drug from the cell, thereby conferr...

IHC

Melan A (Mart1)

Melan A (Mart1, Melanoma Antigen Recognized by T-cells 1), is a differentiation antigen that is expressed in melanocytes, most melanomas. Melan A reco...

IHC

Mesothelin

Mesothelin is a 40kDa cell surface glycoprotein selectively expressed by mesothelial cells and malignant mesotheliomas, as well as by non-mucinous ova...

IHC

MGMT

MGMT (O-6-methylguanine-DNA methyltransferase) is a DNA repair enzyme. MGMT protects cells from alkylating toxins, and is an important factor in drug...

IHC

MITF

MITF (microphthalmia transcription factor) is a transcription factor that regulates the development and survival of melanocytes. MITF is restricted to...

IHC

MLH1

MLH1, a mismatch repair protein involved in maintaining the integrity of genetic information, alongside MSH2, MSH6 and PMS2. During DNA replication, s...

IHC

MMR Panel by IHC (MLH1, MSH2, MSH6, PMS2)

A well-defined subtype of colorectal cancer (CRC) is characterized by a deficiency in the mismatch repair (MMR) pathway. MMR deficiency not only contr...

IHC

MOC31

Monoclonal antibody MOC31 recognizes a membrane glycoprotein of 40kDa present on epithelial cells but not on mesothelial cells. MOC31 reacts with most...

IHC

MPO

Myeloperoxidase (MPO) is an important enzyme used by granulocytes during phagocytic lysis of engulfed foreign particles. In normal tissues and in a va...

IHC

MPO Cytochemical

Special stain (cytochemical). Myeloperoxidase (MPO) is present in granules of myeloid and monocytic cells, but absent from lymphocytes. Therefore MPO ...

IHC

MSA

Muscle Specific Actin (MSA) antibody recognizes the alpha and gamma isotypes of skeletal, cardiac, and smooth muscle cells. It is non-reactive with ot...

IHC

MSH2

Human mismatch repair protein 2 (MSH2) is involved in the initial recognition of mismatched nucleotides during the post replication mismatch repair pr...

IHC

MSH6

Mismatch repair (MMR) genes results in failure to repair errors in repetitive sequences that occur during DNA replication. The defects in DNA r...

IHC

MUC1

Mucin 1 (MUC1) is a high molecular weight glycoprotein that is found on the apical surface of many glandular epithelia, including the gastrointestinal...

IHC

MUC2

Mucin 2 (MUC2) expression is detected in human tissues such as normal colon, breast, prostate, and salivary gland, as well as in gastrointestinal, col...

IHC

MUC4

MUC4 is useful in the identification of low-grade fibromyxoid sarcoma (LGFMS) and sclerosing epithelioid fibrosarcoma.

IHC

MUC5

Mucin 5 (MUC5) is expressed in gastric mucosa, and in gall bladder epithelium. MUC5 antibody is recommended for use as part of a panel of antibodies f...

IHC

MUC6

MUC6 is expressed mucopeptic neck cells and pyloric glands of the gastric mucosa. MUC6 antibody is recommended for use as part of a panel of antibodie...

IHC

Mucicarmine

Special stain. Mucicarmine staining is used to identify epithelial mucins, namely acid mucopolysaccharides. Staining is useful to distinguishing mucin...

IHC

MUM1

The MUM1 antibody is specific for the MUM1/IRF4 protein that is overexpressed in late plasma-cell-directed stages of B-cell differentiation. MUM1 is a...

IHC

MyoD1

Nuclear expression of myogenic differentiation 1 (MyoD1) is restricted to skeletal muscle tissue and has been demonstrated to be a sensitive marker of...

IHC

Myogenin

Expression of myogenin is restricted to cells of skeletal muscle origin. It is a useful marker for tumors of the muscle lineage, being strongly expres...

IHC

Myoglobin

Myoglobin is found in skeletal and cardiac muscle but not in smooth muscle. Because myoglobin appears relatively late in the maturational sequence of ...

IHC

Napsin A

Napsin A has a specific function in normal alveolar epithelium and is proposed to play a role in the proteolytic processing of surfactant precursors. ...

IHC

NB (Neuroblastoma)

This antibody recognizes human neuroblastoma (NB) but does not bind to other small round-cell tumors of childhood. NB reacts with a wide range of norm...

IHC

NeoTYPE™ CUP Consult

A full morphologic/IHC consult for cancer of unknown primary (CUP) is performed by NeoGenomics pathologists with concurrent multi-method NeoTYPE™ Disc...

IHC

NeuN

NeuN is a sensitive and specific marker of neuronal differentiation in brain tumors.

IHC

NF (Neurofilament)

Neurofilaments (NFs) are the intermediate filaments of neurons and their processes. NFs are expressed in tumors of neural origin or tumors displaying ...

IHC

NKX2.2

Homeobox protein NKX2.2 plays a critical role in neuroendocrine/glial differentiation. The NKX2.2 gene was recently identified as a target of E...

IHC

NKX3.1

NKX3.1 is a protein encoded by the NKX3.1 gene located on chromosome 8. NKX3.1 protein has been found to be positive in the vast majority of primary p...

IHC

NSE (Neuron Specific Enolase)

In normal tissue, most neurons and their axonal and dendritic processes stain strongly positive for Neuron Specific Enolase (NSE), with the exception ...

IHC

OCT2

Octamer Binding Transcription Factor 2 (OCT2) is present in all B-cells expressing Ig. The combination of BOB1 and OCT2 stains is helpful in distingu...

IHC

OCT4

Octamer Binding Transcription Factor 4 (OCT4, also known as OCT3/4, POU51) is a transcription factor and is expressed by early embryonic cells, germ c...

IHC

Olig2

Olig2, a transcription factor, is involved in oligodendroglial specification. Olig2 expression has been reported in most glial tumors, such as oligode...

IHC

p120 Catenin

P120 Catenin is a tyrosine kinase which binds to E-cadherin within the cell membrane. It is detectable in the cell membranes of a wide variety of cel...

IHC

p16

p16 (p16 -INK4a, p16-MTS1, inhibitor of CDK4) is the product of the CDKN2 gene. It inhibits the progression of the cell cycle through the G1 ph...

IHC

p21

p21 is a cyclin dependent protein kinase inhibitor and is a member of a family of proteins that functions to slow down cell division. p21 is found in ...

IHC

p27

p27 (KIP1) belongs to the family of cell cycle regulators that cause cell cycle arrest in G1 phase. p27 promotes apoptosis, plays a role in terminal d...

IHC

p40

p40 antibody recognizes δNp63—a p63 isoform. It is equivalent to p63 in sensitivity for squamous cell carcinoma, but it is markedly superior to ...

IHC

P501S

P501S protein, also called the prostein, is a type IIIa plasma membrane protein which is exclusively expressed in cells of normal and malignant prosta...

IHC

P504S

Expression of P504S protein, or Alpha-methylacyl-CoA Racemase (AMACR), is found in prostatic adenocarcinoma but not in benign prostatic tissue. It has...

IHC

p53

The product of the p53 gene is a nuclear phosphoprotein that regulates cell proliferation. Excess accumulation of the mutant p53 gene product results ...

IHC

p57

p57 (Kip 2, CDKN 1C) is an inhibitor of several G1 cyclin complexes and is a negative regulator of cell proliferation. The gene encoding human p57 is ...

IHC

p63

p63 is a homologue of the p53 gene and is necessary for normal breast and prostate development. Unlike other markers of myoepithelial cells and basal ...

IHC

pAKT (Phosphorylated AKT)

AKT is a signal transduction protein that plays a central role in inhibiting apoptosis in a variety of tumor types. Constitutive activation of AKT (p...

IHC

Pan Melanoma (S100 + Melan A + Tyrosinase)

The Pan Melanoma staining combination increases sensitivity for melanomas. Since many skin biopsies are small, the triple stain conserves valuable tis...

IHC

Pan Melanoma/Ki67

Pan Melanoma/Ki67 serves as a tool to identify the proliferation rate of melanocytic lesions. A high Ki67 rate of a melanocytic lesion raises the poss...

IHC

Pancreatic Polypeptide (PP)

Pancreatic polypeptide (PP) is secreted by PP-cells of islet. It is also found in pancreatic acinar tissue and ductal epithelium. This antibody is use...

IHC

Parafibromin

Complete absence of nuclear staining for parafibromin is diagnostic of parathyroid carcinoma or an HPT-JT-related tumor (hyperparathyroidism-jaw tumor...

IHC

Parvovirus

This monoclonal antibody clone, R92F6, recognizes a capsid protein of human parvovirus B19. Therefore, this antibody will be useful in detection of pa...

IHC

PAX2

Paired Box 2 (PAX2) is a transcription factor that is essential for kidney development. In kidneys of normal adult, Pax2 protein expression is limited...

IHC

PAX5

Paired Box 5 (PAX5) is a B-cell specific activator protein (BSAP). In early stages of B-cell development, PAX5 influences the expression of several B-...

IHC

PAX8

The PAX8 gene is a member of the paired box (PAX) family of transcription factors. This family plays critical roles during fetal development an...

IHC

PD1

Programmed death-1 (PD-1) is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PD-1 is a marker of angioimmunoblastic lymphoma and sugg...

IHC

PDGFR Alpha (Platelet Derived Growth Factor Receptor Alpha)

Activated receptors control cell growth, migration and differentiation and may be a useful prognostic marker as well as a therapeutic target for disea...

IHC

PDGFR Beta (Platelet Derived Growth Factor Receptor Beta)

Platelet-derived Growth Factor Receptor Beta (PDGFRB) activated receptors control cell growth, migration and differentiation. This antibody may be a ...

IHC

PD-L1 28-8 FDA (OPDIVO®)

PD-L1 IHC 28-8 pharmDx is a qualitative immunohistochemical assay using Monoclonal Rabbit Anti-PD-L1, clone 28-8 intended for use in the detection of ...

IHC

PD-L1(LDT)

PD-L1 inhibits ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression. PD-L1 is regarded as promising therapeutic target ...

IHC

PD-L1, 22C3 FDA (KEYTRUDA®)

PD-L1 IHC 22C3 pharmDx is a qualitative immunohistochemical assay using Monoclonal Mouse Anti-PD-L1, Clone 22C3 intended for use in the detection of P...

IHC

PD-L1, SP142 FDA (TECENTRIQ®)

The VENTANA PD-L1 (SP142) Assay is a qualitative immunohistochemical assay using rabbit monoclonal anti-PD-L1 clone SP142 intended for use in the a...

IHC

Perforin

Perforin is a protein found in cytoplasmic granules of cytotoxic T-lymphocytes (CTLs). CTLs bind to cells that express foreign antigens and induce the...

IHC

PGP9.5

Protein Gene Product 9.5 (PGP9.5) is also known as ubiquitin C-terminal hydrolase 1 (UCHL-1). Expression of PGP9.5 is highly specific to neurons and t...

IHC

PgR

Progesterone Receptor (PR) belongs to a superfamily of nuclear hormone receptors. Estrogen Receptor (ER) induces PR expression, therefore, PR status s...

IHC

pHistone H3 (PHH3)

Phosphohistone H3 (PHH3) is a marker of cells in the late G2-M phase of the cell cycle. It is not expressed in apoptotic cells which may be confused w...

IHC

PLAP

Normally human Placental Alkaline Phosphatase (PLAP) is produced by syncytiotrophoblasts after the twelfth week of pregnancy. PLAP is expressed by bot...

IHC

PMS2

PMS2, also known as PMS1 protein homologue 2, is a DNA mismatch repair (MMR) protein. The PMS2 protein forms a heterodimer with the MLH1 protein which...

IHC

Pneumocystis Carinii ( Jiroveci)

This antibody is specific to P. carinii (P. Jiroveci). It stains P. carinii distinctly. The staining pattern is visualized as homogeneou...

IHC

Prealbumin (TTR)

Prealbumin (Transthyretin, TTR) is a hormone-binding protein that participates in the plasma transport of both thyroxine and retinol (vitamin A). The ...

IHC

Prolactin

Prolactin is a growth factor secreted by the anterior pituitary that is necessary for the proliferation and differentiation of the mammary glands. Pro...

IHC

Prostate Triple Stain

The combination of p63 + CK HMW + P504S (PIN-4 cocktail) can be extremely useful for diagnosing prostatic intraepithelial neoplasia (PIN) and/or prost...

IHC

PSA

Prostate specific antigen (PSA) is a glycoprotein with a molecular weight of 33-34kDa. It is restricted to the cytoplasm of acinar and ductal epithel...

IHC

PSAP/HPAP

Prostate specific acid phosphatase/human prostatic acid phosphatse (PSAP/HPAP) is a 100kDa glycoprotein present in high concentration in the prostate ...

IHC

PSMA

Prostate specific membrane antigen (PSMA) is a 750 amino acid type II membrane glycoprotein with folate hydrolase and neuropeptidase activity. PSMA is...

IHC

PTEN

Phosphatase and tensin homolog (PTEN) is a tumor suppressor gene that is mutated in a wide range of cancers. PTEN plays a role in cell proliferation, ...

IHC

PTH

Parathyroid hormone (PTH) is expressed in normal parathyroid, parathyroid adenomas and primary and secondary hyperplasia of parathyroid. This antibod...

IHC

PU.1

PU.1 is a transcription factor that has been shown to be important for normal B-cell development. The absence of PU.1 results in a total block of B-ce...

IHC

RB (Retinoblastoma Protein)

Retinoblastoma (RB) is a tumor suppressor gene which functions as a negative regulator of the cell cycle by interacting with transcription fact...

IHC

RCC1

In normal kidney, renal cell carcinoma (RCC1, gp200) is localized along the brush border of the proximal tubule. In other normal tissues, RCC is also ...

IHC

ROS1

ROS1 gene rearrangements are reported in 1% to 2% of lung adenocarcinomas and are associated with a response to the multi-targeted tyrosine kin...

IHC

S100

S100 belongs to the family of calcium binding proteins. Antibody to S100 stains Schwannomas, ependymomas, astrogliomas, almost all benign melanocytic ...

IHC

S100p

Expression of S100P, a member of the S100 family, is increased in a number of tumors, including pancreas, lung, breast, and ovary carcinomas. S100P c...

IHC

SALL4

SALL4, a newly identified zinc-finger transcriptional factor, is required for the maintenance of embryonic stem cell pluripotency by modulating OCT4. ...

IHC

Serotonin

Serotonin is synthesized in serotonergic neurons in the central nervous system and enterochromaffin cells in the gastrointestinal tract and serotonin-...

IHC

SF1

SF1 is expressed in all steroidogenic tissues, including the adrenal cortex, testicular Sertoli cells, and Leydig cells, ovarian theca, hypothalamus, ...

IHC

Simian Virus 40 (SV40)

Simian Virus 40 (SV40) is a polyomavirus that is found in both monkeys and humans. Like other polyomaviruses, SV40 is a DNA virus that has the potent...

IHC

SMA

Smooth muscle actin antibody binds to smooth muscle cells and myoepithelial cells. It stains the muscularis propria and muscularis mucosae of the gast...

IHC

SMMHC

Smooth Muscle Myosin, Heavy Chain (SMMS-1) is an antibody to smooth muscle myosin, heavy chain that reacts with human visceral and vascular smooth mus...

IHC

Smoothelin

Smoothelin is a novel cytoskeletal protein that reacts with the 59 kDa and 100 kDa proteins corresponding to Smoothelin A and B, respectively, which a...

IHC

Somatostatin

Somatostatin is a useful marker of D-cells of pancreatic islet cells. D-cells are used to identify hyperplasia of the pancreatic islets. Most of these...

IHC

Somatostatin (Receptor Type 2)

Somatostatin receptor type 2 (sstr2) is a receptor for somatostatins-14 and -28. This antibody has a great value in the assessment of sst2A status in ...

IHC

SOX10

SOX10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is also a useful marker in detecting both the...

IHC

SOX11

Nuclear protein expression of SOX-11 is highly associated with both cyclin D1-positive and negative mantle cell lymphoma (MCL). SOX-11 IHC is useful f...

IHC

SOX2

SOX2 stains all embryonal carcinomas and is highly specific for squamous cell carcinoma.

IHC

Spirochete

Spirochete (Treponema pallidum) is the causative agent of syphilis. In the past, localization of the spirochete agent was achieved with silver ...

IHC

STAT6

STAT6 is a highly sensitive and specific immunohistochemical marker for solitary fibrous tumor (SFT) and can be helpful to distinguish this tumor type...

IHC

Surfactant

Pulmonary surfactant apoproteins play essential roles in keeping alveoli from collapsing at the end of expiration. SP-A is located mainly in type II p...

IHC

Survivin

Survivin is an anti-apoptotic protein, expressed in the G2/M cell cycle phase. Survivin expression is turned off during fetal development and is not f...

IHC

Synaptophysin

Antibody to synaptophysin reacts with neuroendocrine neoplasms of neural as well as epithelial types. In combination with chromogranin A and NSE antib...

IHC

Tau

Tau is important in establishing and maintaining neuronal morphology and is a major component of the neurofibrillary tangles (NFTs) characteristic of ...

IHC

TCL1

T-cell leukemia/lymphoma protein 1 (TCL1) is normally found in the nucleus and cytoplasm of lymphoid lineage cells during early embryogenesis. Chromos...

IHC

TCRβF1

T Cell Receptor beta (TCRβ) is used as a phenotypic marker for TCRβ expressing T-cells. TCRβ is expressed by thymocytes and a majority of periphera...

IHC

TdT (Terminal Deoxynucleotidyl Transferase)

TdT is a highly specific marker for the diagnosis and classification of acute lymphoblastic lymphoma/leukemias. The determination of TdT expression is...

IHC

TFE3

Overexpression of TFE3 is a sensitive and specific marker of Xp11 translocation in renal cell carcinomas. TFE3 is also expressed in alveolar soft par...

IHC

TGF Alpha (Transforming Growth Factor Alpha)

Transforming growth factor (TGF)-α is a polypeptide growth factor that binds to the epidermal growth factor receptor and is thought to stimulate...

IHC

Thrombomodulin (TM)

Thrombomodulin (TM) is a plasma membrane-related glycoprotein that has anticoagulant activity. TM antigen is found in several cell types, including m...

IHC

Thyroglobulin (TGB)

This antibody labels thyroglobulin (TGB) in follicular epithelial cells of the thyroid and colloid. Thyroglobulin antibody is useful in positive ident...

IHC

TIA1

TIA1 (T-cell intracytoplasmic antigen) monoclonal antibody reacts with a 15 kDa cytoplasmic granule-associated protein, expressed in lymphocytes proce...

IHC

TLE1

Expression of the transducing-like receptor (TLE) genes, TLE1, TLE2, TLE3 and TLE4, correlate with immature epithelial cells that...

IHC

Toxoplasma

Toxoplasma is a crescent shaped sporozoan that lives as an intracellular parasite in various tissues of vertebrates and completes its life cycle in a ...

IHC

TRAcP

Special stain.

IHC

Trichrome

Special stain. Trichrome stains are frequently used to differentiate between collagen and smooth muscle in tumors and to identify increases in collage...

IHC

Tryptase

This antibody labels a mast cell tryptase. It will also show reactivity to basophils, but to a lesser degree.

IHC

TS (Thymidylate Synthase)

Antibody MAB4130 recognizes a 36 kDa protein identified as Thymidylate Synthase [TS], which is a target for the fluoropyrimidine group of antineoplast...

IHC

TSH

Thyroid Stimulating Hormone (TSH) is a pituitary hormone of 28 kDa that stimulates thyroid growth and production of thyroid hormones. This antibody la...

IHC

TTF1

Thyroid Transcription Factory (TTF1) is found only in thyroid and thyroid tumors regardless of histologic type, as well as in lung carcinomas, includ...

IHC

Tuberculosis

Mycobacterium tuberculosis is the most common cause of tuberculosis. Immunohistochemical demonstration of mycobacterial antigens is not only us...

IHC

Tyrosinase

Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway. Mutations of the tyros...

IHC

Uroplakin II

Uroplakin II is a 15 kDa protein component of urothelial plaques. Uroplakin II mRNA was found in both bladder cancer tissues and peripheral blood of p...

IHC

Uroplakin III

Uroplakins (UPs) are a family of transmembrane proteins (UPs Ia, Ib, II and III) that are specific differentiation products of urothelial cells. In no...

IHC

Varicella Zoster Virus (VZV)

Varicella Zoster Virus (VZV), a member of the human herpes virus family, causes two distinct clinical manifestations: chickenpox and shingles. Primar...

IHC

Vascular Endothelial Growth Factor (VEGF)

Vascular endothelial growth factor (VEGF) is a glycoprotein involved in angiogenesis that promotes tumor progression and metastasis. VEGF is a mitogen...

IHC

Villin

This antibody recognizes villin, a cytoskeletal filament protein of 58 kDa found in human renal epithelial cells. Villin antibody is useful for the st...

IHC

Vimentin

Vimentin is the major intermediate filament in a variety of mesenchymal cells, including endothelial cells, all fibroblastic cells, macrophages, Serto...

IHC

Warthin Starry

Special stain. Warthin Starry stain is intended to identify Helicobacter pylori and spirochete microorganisms in tissue samples.

IHC

Wright Giemsa

Special stain. The Wright Giemsa stain is used to stain peripheral blood and bone marrow smears for study of blood cell morphology.

IHC

WT1

Wilms tumor susceptibility gene 1 protein (WT1) has diagnostic utility in the distinction of mesothelioma from adenocarcinoma in tissue sections of pl...

IHC

ZAP70

A prognostic factor in CLL/SLL.

IHC

My Favorite Tests

Please select your favorite tests to print a custom catalog. As you browse our test menu, and you see your preferred test, simply select the Add to Favorites button.
NOTE: This is a cookie-based feature. If you delete your browser cookies, you will need to rebuild your test list.

Downloads