Methodology
Immunohistochemistry (IHC)
Test Description
Cytokeratin 18 (CK 18), a 45kDa protein, belongs to the acidic type of cytokeratins, and is typically expressed in simple, nonstratified epithelia. However, CK 18 is also expressed in basal and superficial cells of transitional epithelium, as well as in the luminal/secretory cells of complex epithelia.
Specimen Requirements
- A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type
or - One (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody ordered
- Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Storage & Transportation
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.
CPT Code(s)*
88342 x 1 or 88341 x 1
Turnaround Time
24 hours
Level of Service
Stain Only
New York Approved
Yes