Test by Disease - Acute myeloid leukemia (AML)

73 Tests in Listing


AML Add-On Flow Panel

Available as global and tech-only. This add-on panel is available to clarify findings on samples currently having flow cytometry analysis at NeoGenom...

Flow

AML Favorable-Risk Panel

Probes: RUNX1/RUNX1T1 (ETO/AML1) t(8;21) | PML/RARA t(15;17) | CBFB inv(16), t(16;16)
Disease(s): Acute myelo...

FISH

AML FISH Panel (New York)

Probes: 5q-, -5 (5p15.2, 5q33-34) | 7q-, -7 (7q31, Cen 7) | Trisomy 8 (Cen 8) | MLL (11q23) | RUNX1T1/RUNX1 (ETO/AML1) t(8;21) | P...

FISH

AML Follow-Up Flow Panel

Available as global and tech-only. Prior immunophenotyping at NeoGenomics with Standard or Extended Flow Panel is strongly recommended. Clients who...

Flow

AML Non-Favorable Risk FISH Panel

Probes: RPN1, MECOM (3q21, 3q26.2) | 5q-, -5 (5p15, 5q31, 5q33 | 7q-, -7 (Cen 7, 7q22, 7q31) | Trisomy 8 (Cen 8) | DEK/NUP214 (CAN...

FISH

AML Reflex Panel

Routine cytogenetics with automatic addition of the NeoTYPE™ AML Prognostic Profile when cytogenetics results show intermediate risk including normal ...

Molecular

AML Standard FISH Panel

Probes: 5q-, -5 (5p15, 5q31, 5q33) | 7q-, -7 (Cen 7, 7q22, 7q31) | Trisomy 8 (Cen 8) | MLL (11q23) | 20q- (20q12, 20qter) | RUNX1...

FISH

ASXL1 Mutation Analysis

Bi-directional sequencing of the majority of exons 13 and 14 of ASXL1, corresponding to amino acids 406-1396.

Molecular

CBFB inv(16)

Probes: CBFB inv(16), t(16;16)
Disease(s): AML, AMML (AML-M4E)

FISH

CBL Mutation Analysis

Bi-directional sequencing of exons 8 and 9 of the CBL gene.

Molecular

CD11c

In normal cells, CD11c is expressed on activated CD4/CD8+ T cells, granulocytes, lymphocytes, macrophages, and NK cells.

In diseased, c...

IHC

CD123

CD123 labels plasmacytoid dendritic cells and is useful in diagnosing neoplasms derived from these cells as well as reactive conditions, such as hist...

IHC

CD3

The CD3 antigen is first detectable in early thymocytes and its appearance probably represents one of the earliest signs of commitment to the T-cell l...

IHC

CD33

CD33 is a useful marker to identify cells of myeloid and monocytic lineage, leukemias and myeloproliferative neoplasms derived from these cells.

IHC

CD34

CD34, a single chain transmembrane glycoprotein, is selectively expressed on human lymphoid and myeloid hematopoietic progenitor cells and endothelial...

IHC

CD61

CD61 (GPIIIa) is a glycoprotein found on megakaryocytes, platelets, and their precursors. CD61 antigen plays a role in platelet aggregation and also a...

IHC

CD79a

CD79a first appears at the pre B-cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found ...

IHC

Chromosome Analysis

A wide variety of abnormalities can be identified, providing both diagnostic and prognostic information. Acute leukemias, lymphomas and chronic mye...

Cytogenetics

DNMT3A Mutation Analysis

Bi-directional sequencing of exon 26, a mutation hotspot region containing R882 and other mutations. In hematological disease, testing may be performe...

Molecular

Erythroid-Mega Add-On Flow Panel

Available as global and tech-only. This add-on panel is available to clarify findings on samples currently having flow cytometry analysis at NeoGenom...

Flow

ETV6 Mutation Analysis

Bi-directional sequencing of exons 2-7 of the ETV6 gene (formerly called TEL). This assay detects sequence variants rather than ETV6 translocations.

Molecular

ETV6-RUNX1 (TEL-AML1) Translocation, t(12;21)

Real-time RT-PCR for quantitative detection of the t(12;21) ETV6-RUNX1 fusion transcript (formerly called TEL-AML1). Analytical sensitivity is 1 tumor...

Molecular

EZH2 Mutation Analysis

Bi-directional sequencing of exons 3-13 and 15-18 of the EZH2 gene.

Molecular

FLT3 Mutation Analysis

Detection of internal tandem duplication and exon 20 tyrosine kinase domain (TKD) mutations using bi-directional sequencing. Positive results identify...

Molecular

Glycophorin A

Glycophorin A (sialoglycoprotein alpha) is one of two transmembrane proteins exposed on the outer surface of normal human erythrocytes. This monoclona...

IHC

Hemoglobin A

Hemoglobin A antibody reacts with the alpha chain of adult hemoglobin A. This antibody is useful in the detection of red blood cell precursors. Immuno...

IHC

HLADR

This antibody to the humn leukocyte antigen (HLA) MHC class II surface antigen stains a variety of cells expressing the HLADR antigen including B-lymp...

IHC

IDH1 & IDH2 Mutation Analysis

Bi-directional sequencing of the exon 4 mutation hotspot regions in both the IDH1 and IHD2 genes. IDH1 and IDH2 are analyzed concurrently. In hemat...

Molecular

inv(16), CBFB-MYH11 Translocation

Real-time RT-PCR for quantitative detection of the inv(16) CBFB-MYH11 fusion transcript. Positive results are reported as ratio of the amount of fusio...

Molecular

Ki67

Ki67 is a nuclear protein that is expressed in proliferating cells. Ki67 is preferentially expressed during late G1, S, M, and G2 phases of the cell ...

IHC

Ki67/Caspase 3 (Double Stain)

The Ki67/caspase-3 antibody cocktail was designed to provide information on apoptosis versus cell proliferation rates. The Ki67 is associated with cel...

IHC

Lysozyme

Lysozyme is synthesized predominantly in reactive histiocytes rather than in resting, unstimulated phagocytes. This antibody labels myeloid cells, his...

IHC

MET (c-MET) Mutation Analysis

Bi-directional Sanger sequencing of MET is performed using PCR primers designed to target hotspot mutations in exons 14, 16, 17 and 19.

Molecular

MLL (11q23)

Probes: MLL (11q23)
Disease(s): ALL, AML

FISH

MPO

Myeloperoxidase (MPO) is an important enzyme used by granulocytes during phagocytic lysis of engulfed foreign particles. In normal tissues and in a va...

IHC

NeoARRAY™ SNP/Cytogenetic Profile

The NeoARRAY SNP/Cytogenetic Profile is available for hematological, solid tumor, and pregnancy loss indications. With the best genome-wide coverage a...

Molecular

NeoARRAY™ SNP/Cytogenetic Profile

The NeoARRAY SNP/Cytogenetic Profile is available for hematological, solid tumor, and pregnancy loss indications. With the best genome-wide coverage a...

Cytogenetics

NeoLAB™ AML Profile - Liquid Biopsy

This test is performed by sequencing of select exons of the genes listed using cell-free plasma DNA/RNA. ASXL1, BCOR, BRAF, CEBPA, CSF3R, DNMT3A, E...

Molecular

NeoLAB™ FLT3 Mutation Analysis - Liquid Biopsy

Detection of internal tandem duplication and exon 20 tyrosine kinase domain (TKD) mutations using bidirectional sequencing. Positive results identify ...

Molecular

NeoLAB™ IDH1 Mutation Analysis - Liquid Biopsy

Bi-directional sequencing of the exon 4 mutation hotspot region in the IDH1 gene. Testing is performed on cell-free plasma DNA/RNA to increase sens...

Molecular

NeoLAB™ IDH2 Mutation Analysis - Liquid Biopsy

Bi-directional sequencing of the exon 4 mutation hotspot region in the IDH2 gene. Testing is performed on cell-free plasma DNA/RNA to increase sensit...

Molecular

NeoLAB™ inv(16), CBFB-MYH11 Translocation - Liquid Biopsy

Real-time RT-PCR for quantitative detection of the inv(16) CBFB-MYH11 fusion transcript using cell-free plasma DNA/RNA. This assay identifies type A f...

Molecular

NeoLAB™ KIT (c-KIT) Mutation Analysis - Liquid Biopsy

Bi-directional sequencing of KIT exons 8, 9, 11, 13 and 17 for detection of activating mutations including the common mutation D816V. Testing is perfo...

Molecular

NeoLAB™ KRAS Mutation Analysis - Liquid Biopsy

Bi-directional sequencing of exons 2 and 3 of the KRAS gene. High-sensitivity sequencing is used for enhanced detection of mutations in codons 12, 13,...

Molecular

NeoLAB™ Myeloid Disorders Profile - Liquid Biopsy

This test is performed on cell-free DNA/RNA in peripheral blood plasma by sequencing select exons of the genes listed. ABL1, ASXL1, ATRX, BCOR, BCO...

Molecular

NeoLAB™ NPM1 Mutation Analysis - Liquid Biopsy

PCR and fragment analysis of exon 12 of the NPM1 gene to detect small insertion mutations specific to AML. Positive results are reported quantitativel...

Molecular

NeoLAB™ NRAS Mutation Analysis - Liquid Biopsy

Bi-directional sequencing of NRAS exons 2 and 3 which includes sites of common activating mutations in codons 12, 13, 59, and 61. Testing is performed...

Molecular

NeoLAB™ PML-RARA Translocation, t(15;17) - Liquid Biopsy

Real-time RT-PCR for quantitative detection of the t(15;17) PML-RARA fusion transcript using cell-free plasma DNA/RNA. Both long and short isoforms of...

Molecular

NeoLAB™ RUNX1-RUNX1T1 (AML1-ETO) Translocation, t(8;21) - Liquid Biopsy

Real-time RT-PCR for quantitative detection of the t(8;21) RUNX1-RUNX1T1 fusion transcript (formerly called AML1-ETO) using cell-free plasma DNA/RNA.

Molecular

NeoTYPE™ AML Favorable-Risk Profile

This test is performed by sequencing of select exons of the genes FLT3 and KIT. Test orders include summary interpretation of all results together....

Molecular

NeoTYPE™ AML Prognostic Profile

This test is performed by sequencing of select exons of the genes listed. ASXL1, BCOR, BRAF, CEBPA, CSF3R, DNMT3A, ETV6, EZH2, FLT3, HRAS, IDH1, ID...

Molecular

NeoTYPE™ Cancer Exome Profile

The NeoTYPE™ Cancer Exome Profile is performed by massive parallel sequencing of the coding regions in 4813 different cancer related genes. Test order...

Molecular

NeoTYPE™ Myeloid Disorders Profile

This test is performed by the sequencing of select exons of the genes listed. ABL1, ASXL1, ATRX, BCOR, BCORL1, BRAF, CALR, CBL, CBLB, CBLC, CDKN2A,...

Molecular

NPM1 Mutation Analysis

PCR and fragment analysis of exon 12 of the NPM1 gene to detect small insertion mutations specific to AML. Positive results are reported quantitativel...

Molecular

NRAS Exon 4 Mutation Analysis

Bi-directional sequencing of NRAS exon 4 is performed using PCR primers designed to target hotspot mutations in codons 117 and 146, among other reg...

Molecular

NRAS Mutation Analysis

Bi-directional sequencing of NRAS exons 2 and 3 which includes sites of common activating mutations in codons 12, 13, 59, and 61.

Molecular

PAX5

Paired Box 5 (PAX5) is a B-cell specific activator protein (BSAP). In early stages of B-cell development, PAX5 influences the expression of several B-...

IHC

PML-RARA Translocation, t(15;17)

Real-time RT-PCR for quantitative detection of the t(15;17) PML-RARA fusion transcript. Both long and short isoforms of the fusion transcript are d...

Molecular

PTPN11 Mutation Analysis

Bi-directional sequencing of exons 2-4 of PTPN11.

Molecular

RUNX1 Mutation Analysis

Bi-directional sequencing of exons 4-10 of the RUNX1 gene

Molecular

RUNX1-RUNX1T1 (AML1-ETO) Translocation, t(8;21)

Real-time RT-PCR for quantitative detection of the t(8;21) RUNX1-RUNX1T1 fusion transcript (formerly called AML1-ETO). Analytical sensitivity is 1 tum...

Molecular

RUNX1T1/RUNX1 (ETO/AML1) t(8;21)

Probes: RUNX1T1/RUNX1 (ETO/AML1) t(8;21)
Disease(s): AML-M2

FISH

SETBP1 Mutation Analysis

Bi-directional sequencing of the SETBP1 exon 4 mutation hotspot (covering amino acids 823-941). The locked nucleic acid (LNA) technique is used to inc...

Molecular

SF3B1 Mutation Analysis

RT-PCR and bi-directional sequencing of exons 14-17 of the SF3B1 gene. More than 90% of reported mutations are detected in these exons. This test dete...

Molecular

SRSF2 Mutation Analysis

Bi-directional sequencing of the mutation hotspot region in exon 1 of the SRSF2 gene corresponding to amino acids 57-120.

Molecular

Standard Leukemia/Lymphoma Panel - 24 markers

Available as global and tech-only. Markers are CD2, CD3, CD4, CD5, CD7, CD8, CD10, CD11c, CD13, CD14, CD16, CD19, CD20, CD23, CD33, CD34, CD38, CD45,...

Flow

TET2 Mutation Analysis

Bi-directional sequencing of the entire coding sequence of the TET2 transcript variant A (2002 amino acids in length).

Molecular

TP53 Mutation Analysis

Bi-directional sequencing of TP53 exons 4-9.

Molecular

U2AF1 Mutation Analysis

Bi-directional sequencing of exons 2 and 7 of the U2AF1 gene (also called U2AF35).

Molecular

Universal Fusion/Expression Profile

The Universal Fusion/Expression Profile is a targeted RNA sequencing panel that utilizes next-generation sequencing (NGS) to detect all relevant fu...

Molecular

Wright Giemsa

Special stain. The Wright Giemsa stain is used to stain peripheral blood and bone marrow smears for study of blood cell morphology.

IHC

WT1 Mutation Analysis

Bi-directional sequencing of exons 7 and 9 is performed for detection of sequence variant mutations.  Fra...

Molecular

ZRSR2 Mutation Analysis

Bi-directional sequencing of exons 5 and 7-11 of the ZRSR2 gene.

Molecular

 

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