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All our NeoSeq offerings are high quality paired-end high depth Illumina-based sequencing in a CAP/CLIA approved laboratory in addition to secure access to our analysis pipeline.
Figure 1. A clinical grade mutation calling pipeline for NeoSEQ takes advantage of three different algorithms (A-C) to identify clinically significant somatic SNVs and small indels at 1-5% Allele frequency. 498 cancers from different patients were sequenced with either a NeoSEQ Myeloid or NeoSEQ Tumor gene panel depending on the disease. Each case was individually analyzed and clinical reports were written for the 326 mutations observed. The default clinical grade pipeline can be further optimized and additional mutations can be discovered by using the advanced options. The pipeline is free to use for clients.
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