Molecular
B-Cell Gene Rearrangement Alternative Name B-Cell Translocations Methodology Molecular Test Description Detection of clonal IgH gene rearragements by PCR of IgH…
Immunohistochemistry (IHC)
BCL1/Cyclin D1 Methodology Immunohistochemistry (IHC) Test Description BCL1/Cyclin D1 is a nuclear protein detectable in formalin-fixed, paraffin-embedded (FFPE) sections and is found in the majority…
Molecular
BTK Inhibitor Acquired Resistance Panel Alternative Name BTK, BTK acquired resistance Methodology Molecular Test Description Concurrent bi-directional sequencing of…
FISH
CCND1(BCL1)/IgH t(11;14) Methodology FISH Test Description Probes: CCND1/IgH t(11;14) Disease(s): Mantle cell lymphoma, NHL, multiple myeloma Clinical Significance…
Immunohistochemistry (IHC)
CD19 Methodology Immunohistochemistry (IHC) Test Description CD19 recognizes a 95kD cell surface glycoprotein which is expressed by cells of the B-cell lineage and follicular dendritic cells. CD19 is…
Immunohistochemistry (IHC)
CD20 Methodology Immunohistochemistry (IHC) Test Description Normal cell expression of CD20 is found on most B-cells (after CD19 and CD10 expression, before CD21/22 expression and surface…
Immunohistochemistry (IHC)
CD22 Methodology Immunohistochemistry (IHC) Test Description CD22 expression is restricted to normal and neoplastic B-cells and is absent from other hemopoietic cell types. In B-cell ontogeny, CD22 is…
Immunohistochemistry (IHC)
CD3 Methodology Immunohistochemistry (IHC) Test Description The CD3 antigen is first detectable in early thymocytes and its appearance probably represents one of the earliest signs of commitment to…
Immunohistochemistry (IHC)
CD5 Methodology Immunohistochemistry (IHC) Test Description CD5, a transmembrane protein, is found on most thymocytes and immature peripheral T-cells. It stains normal B-cells of mantle zone of spleen…
Immunohistochemistry (IHC)
CD79a Methodology Immunohistochemistry (IHC) Test Description CD79a first appears at the pre B-cell stage and persists until the plasma cell stage where it is found as an intracellular component.…
Flow Cytometry
CLL/Mantle Cell Companion Add-On Flow Panel Methodology Flow Cytometry Test Description Available as global and tech-only. This add-on panel is available to clarify findings on samples currently…
Cytogenetics, FISH, Flow Cytometry, Immunohistochemistry (IHC), Molecular
COMPASS® Hematopathology Services Alternative Name COMPASS® Bone Marrow Evaluation, COMPASS® Peripheral Blood Evaluation Methodology Cytogenetics FISH Flow Cytometry…
Cytogenetics, FISH, Flow Cytometry, Immunohistochemistry (IHC), Molecular
COMPASS® Select Hematopathology Services Alternative Name COMPASS® Select Bone Marrow Evaluation, COMPASS® Select Peripheral Blood Evaluation Methodology Cytogenetics FISH Flow Cytometry…
Immunohistochemistry (IHC)
FOXP1 Methodology Immunohistochemistry (IHC) Test Description FOX P1 (Forkheadbox-P1) is a transcription factor widely expressed in normal tissues. Its expression is commonly deregulated in…
FISH
High-Grade B-Cell Lymphoma Reflex FISH Panel Methodology FISH Test Description Probes: MYC (8q24) | MYC/IgH/CEN8 t(8;14) Reflex Scheme: Reflex to BCL2 (18q21) and BCL6 (3q27) if MYC/IgH/CEN8 t(8;14)…
FISH
High-Grade/Large B-Cell Lymphoma Panel (NY and non-NY) Alternative Name Large B-Cell Lymphoma Methodology FISH Test Description Probes: BCL6 (3q27) | MYC (8q24) | BCL2…
Immunohistochemistry (IHC)
IgD Alternative Name Immunoglobulin D Methodology Immunohistochemistry (IHC) Test Description IgD antibody reacts with immunoglobulin Ig delta chains. This antibody is…
FISH
IgH (14q32) Alternative Name Immunoglobulin heavy chain Methodology FISH Test Description Probes: IgH (14q32) Disease(s): Lymphoma, NHL, multiple myeloma, MGUS…
Molecular
IgH Clonality by NGS Methodology Molecular Test Description The IgH Clonality by NGS assay detects clonal populations of B-lymphocytes in a given patient sample through the analysis of the VDJ segment…
Immunohistochemistry (IHC)
IgM Alternative Name Immunoglobulin M Methodology Immunohistochemistry (IHC) Test Description IgM antibody reacts with immunoglobulin Ig mu chains. This antibody is…
Immunohistochemistry (IHC)
Ki-67 Methodology Immunohistochemistry (IHC) Test Description Ki67 is a nuclear protein that is expressed in proliferating cells. Ki67 is preferentially expressed during late G1, S, M, and G2 phases…
Immunohistochemistry (IHC)
LEF1 Methodology Immunohistochemistry (IHC) Test Description LEF1 overexpression is highly associated with CLL/SLL among small B-cell lymphomas and may serve as a useful marker for diagnosis and…
FISH
Low-Grade/Small B-Cell Lymphoma FISH Panel Alternative Name Small B-Cell Lymphoma Methodology FISH Test Description Probes: BCL6 (3q27) | CCND1/IgH t(11;14) IgH/BCL2 t…
FISH, Flow Cytometry, Immunohistochemistry (IHC), Molecular, Morphologic Evaluation
Lymphoma Consult Methodology FISH Flow Cytometry Immunohistochemistry (IHC) Molecular Morphologic Evaluation Test Description Lymphoma diagnoses may be…
Molecular
Neo Comprehensive™ - Heme Cancers Alternative Name Neo Comprehensive Heme, Neo Comp Heme, Heme CGP Methodology Molecular Test Description The Neo Comprehensive™ - Heme…